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ORAL vs INTRAVENOUS (IV)

Why should you go through the trouble and cost of doing IV nutrient therapy when you can purchase over-the-counter oral supplements and take them at the comfort of your own home?

It's a question that our employees gets asked a lot when people are weighing the advantages of IV therapy.

I know that it seems counterintuitive to go to a wellness spa for IV therapy when supplements appear to be everywhere nowadays and can be readily obtained by opening a drawer in your home, however there are in fact many scientific reasons to change your present oral supplementation of important vitamins and minerals.

Much of this comes down to a basic notion: Bioavailability and Absorption.

The IV Route

An IV infusion separates itself since it provides 100% of every vitamin straight in your bloodstream. It is possible to unwind in a recliner while we flooding your veins and cells right with nourishing vitamins and nutrients. Luckily, this implies your gut does not need to experience the work of breaking food down into its constituent vitamins, minerals, nutrients, and amino acids. Furthermore, your gut does not need to pass them through its walls and your own cells do not need to find those molecules.

The very best way to describe it is that IV therapy is similar to the urgent care of Functional Medicine. It allows for an instant impact in addition to producing long lasting effects that help you feel your best for days and sometimes weeks ahead of time.

The Oral Route

If you choose a vitamin by mouth, then your body needs to perform plenty of effort to move that vitamin to the bloodstream. The approach is in fact fairly intricate and rather inefficient relative to direct infusions.

Water-soluble vitamins, for instance, are big molecules. They can not only pass out of your intestines right into the bloodstream such as IV vitamins can. Rather they need to cross your "enterocytes" or "colonocytes"-- the layer of cells lining the whole intestinal tract. These cells possess phospholipid cell membranes which are initially impenetrable to water soluble vitamins and nutrients.

Unless you have already found liposomal vitamins that are wrapped in the very same phospholipids making up the cell membranes, the more "regular" water soluble vitamins really require particular "transporters" to move each individual nutrient across the cells lining the intestinal tract.

One transporter is popularly known as the sodium-dependent multivitamin transporter (SMVT). Consider this SMVT (or some other multivitamin transporter) such as the TSA agents that enable you to board your plane. They allow certain people to get through while forbidding others. In cases like this the people are vitamins seeking to cross the border to get out of your gut into your blood.

Not only are those SMVT transporters restricted in ability, the SMVT modulates the absorption of many vitamins and nutrients: Biotin (vitamin B1) significant in hair, skin, and nail integrity and immune function, pantothenic acid (vitamin B5) and alpha lipoic acid (ALA) -- a crucial antioxidant.

Since it's responsible for the transportation of many nutrients this means each of these must get in line waiting to cross the border into your circulation. This implies oral vitamins compete with each other for access into the bloodstream and many pass before gaining entry. So your bioavailability is as low as 20% and you don't absorb almost the quantity that could.

There are naturally additional transporters for different vitamins which perform exactly the same "passport control" function to receive that vitamin in the intestine into circulation.

Thiamine (vitamin B3) -- a vitamin important in cardiovascular and neurologic role --utilizes transporters known as thiamine. Chronic alcohol intake, as an example, significantly inhibits absorption of vitamin B3. E. coli infections also cause a substantial inhibition of both thiamine uptake too.

Riboflavin (vitamin B2) -- critical in the creation of energy (ATP) in mitochondria and to the regeneration of folate (vitamin B9) to its active form. Chronic alcohol ingestion, in addition to some drugs, can substantially inhibit absorption of vitamin B2.

As you've read so far, oral supplementation is currently hard, because unless you're carrying a very special type of nutritional supplements (liposomal), it is likely to be challenging for those vitamins to cross out of your gut into your bloodstream. This can be further complicated by the "transportation" channels that behave like TSA agents from your gut to your blood where vitamins need to line up and compete with one another for priority positioning. In addition to this, the transporter molecules themselves may be affected by a broad range of lifestyle and dietary factors that affect their abundance and their efficacy.

Put simply, oral supplements aren't so effective or bioavailable for your entire body.

Unfortunately, the issues do not stop there...

Disposition and Infection Affect the Intestinal Lining

The cells lining the intestinal tract, which execute the role of transporting nutrients and vitamins, must be healthy and undamaged for good absorption of vitamins to happen.

As pointed out previously, the absorption of thiamine (B3), riboflavin (B2) and other vitamins is seriously inhibited by chronic alcohol intake. Alcohol is inflammatory and detrimental to the tissues lining the gut and intestines in which absorption of vitamins occurs. Other things that help determine the integrity and purpose of the intestinal lining include:

  • Stress
  • Drugs -- i.e. Ibuprofen and aspirin
  • Diseases -- such as E.coli, Pseudomonas, along with Clostridium
  • Inflammation -- from diabetes, Crohn's disease, ulcerative colitis, and other ailments
  • Smoking

Anything that adversely affects the lining of your gut also negatively affects your ability to absorb nutrients through that lining. The majority of individuals don't have perfect gut barrier function and this also makes oral pills much less effective.

Oral vitamin supplementation is:

  • Basing on crossing the tissues forming intestinal lining for absorption into the circulation.
  • Dependent on a complete intestinal lining that may be easily ruined by alcohol, stress, infections and drugs.
  • Reliant on particular transporters for every vitamin that are sensitive to alcohol usage and therefore are "aggressive" as many vitamins attempt to utilize exactly the same transporter.
  • Less costly but additionally not as efficient in comparison to IV infusions

Intravenous (IV) supplements and vitamins:

  • Bypass absorption entirely making them instantly 100% bioavailable for you.
  • Deliver high levels of nourishing vitamins unattainable together with the dental route.
  • Is all but painless with the usage of pediatric sized needles such as our spa applies use.
  • Is costlier but is typically well worth it for those people who have symptoms of vitamin deficiencies such as tiredness, headaches, weight gain, frequent infections, dry skin that is fragile, brittle nails and hair, and much more.
  • Could have an instantaneous effect on your health--they're like the urgent care of practical and integrative medicine.

Realize that Invigorate Health is not saying oral nutritional supplements are "bad." In reality, they may be an excellent adjunct to treatment, particularly in the event that you utilize liposomal nutritional supplements. But they're in no way is it a replacement or equal of IV therapy.